Class: MolecularModification

Molecular modification is chemical alteration of a known and previously characterized lead compound for the purpose of enhancing its usefulness as a drug. This could mean enhancing its specificity for a particular body target site, increasing its potency, improving its rate and extent of absorption, modifying to advantage its time course in the body, reducing its toxicity, changing its physical or chemical properties (like solubility) to provide desired features.

URI: sio:MolecularModification

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Parents

  • is_a: ChemicalReaction - A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.

Attributes

Inherited from ChemicalReaction:

  • hasCreator 0..1
    • Description: has creator is a relation between an entity and that which created it.
    • Range: Entity

  • hasAttribute 0..1

    • Description: has attribute is a relation that associates a entity with an attribute where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type.

    • Range: Entity

    • satisfies 0..1

    • Description: satisfies is a relation between an entity and the specification or objective that it conforms to.

    • Range: Description

    • isRelatedTo 0..1
    • Description: A is related to B iff there is some relation between A and B.
    • Range: Entity
    • hasParticipant 0..1

    • Description: has participant is a relation that describes the participation of the object in the (processual) subject.

    • Range: Entity